Thermo Fisher Scientific PTPRE Polyclonal Antibody
Rabbit polyclonal antibody targeting human PTPRE protein. Validated for IHC (paraffin) applications. Recognizes cytoplasmic domain peptide. Suitable for research use only. Supplied as liquid, 0.3 mg/mL, store at 4°C or -20°C.
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- PA534140
- 판매단위
- pk
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Applications and Tested Dilution
- Application: Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 3–32 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from cytoplasmic domain of human PTPRE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551493 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gibbon (100%); Monkey (94%); Marmoset, Rat, Hamster, Panda, Dog, Bovine (89%); Mouse, Horse (83%).
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants of this gene have been reported:
- A receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- A nonreceptor-type isoform containing a distinct hydrophilic N-terminus.
Studies in mice suggest regulatory roles of this PTP in RAS-related signaling pathways, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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