Thermo Fisher Scientific Integrin beta 7 Recombinant Rat Monoclonal Antibody (FIB504)
Integrin beta 7 단백질을 인식하는 랫트 유래 재조합 단클론 항체. 인간 및 마우스 반응성. ICC/IF, Flow Cytometry, Inhibition Assay에 사용 가능. Protein A 정제, 1 mg/mL 농도, PBS buffer에 ProClin 300 포함. 연구용 전용.
- 카탈로그번호
- MA548014
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Integrin beta 7 Recombinant Rat Monoclonal Antibody (FIB504)
Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| Inhibition Assays (IA) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FIB504 |
| Immunogen | FIB504 was prepared by immunizing rats with TK1 cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074457 |
Product Specific Information
Specificity: FIB504 recognizes an epitope on integrin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and partially with the epitope defined by FIB21 and FIB22.
Target Information
Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin (LPAM-1), expressed on intraepithelial lymphocytes.
It also associates with alpha E (CD103) to form the alpha E beta 7 integrin (HML-1), expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes.
Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1, and fibronectin, while the ligand of HML-1 is E-cadherin (CD324).
Integrin beta 7 plays an important role in leukocyte adhesion to endothelial cells and promotes transmigration of leukocytes to extravascular spaces during the inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.