Thermo Fisher Scientific CD39 Monoclonal Antibody (24DMS1), Brilliant Ultra Violet 805, eBioscience

Applications and Tested Dilution

• Application: Flow Cytometry (Flow)
• Tested Dilution: 1.0 µg/test

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 700
• eFluor 660
• Functional Grade
• PE
• PE-Cyanine7
• PE-eFluor 610
• PerCP-eFluor 710
• Super Bright 436
• Super Bright 600
• Super Bright 702
• Request custom conjugation

Product Specific Information

The 24DMS1 monoclonal antibody reacts with mouse CD39 (NTPDaseI), an enzyme that converts nucleoside tri- and diphosphates into monophosphates, removing toxic extracellular ATP and ADP.
CD39 plays a key role in inflammation suppression and platelet activation control. It is expressed on B cells, Langerhans cells, monocytes, and CD4⁺CD25⁺FoxP3⁺ Treg cells.
Treg cells lacking CD39 show reduced suppressive function both in vitro and in vivo.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Mouse splenocytes, ≤1.0 µg/test
• Recommended use: Titrate for optimal performance
• Emission: 797 nm (BUV805)
• Laser: Ultraviolet (355 nm)

When using multiple polymer dye-conjugated antibodies (e.g., Super Bright, Brilliant Violet™, Brilliant Ultra Violet™), use Super Bright Complete Staining Buffer (SB-4401) or Brilliant Stain Buffer (00-4409-75) to minimize non-specific interactions.

Light sensitivity: Protect from light to prevent photo-induced oxidation.
Fixation: Samples can be stored in IC Fixation Buffer (00-8222) or 1-step Fix/Lyse Solution (00-5333) up to 3 days at 4°C in the dark.
Methanol compatibility: Short-term methanol fixation is acceptable; avoid storage >1 hour in methanol buffers.

Trademark notice: BRILLIANT ULTRA VIOLET™ is a trademark of Becton, Dickinson and Company and used under license. Powered by Sirigen™.

Target Information

CD39 is a 70–100 kDa surface molecule expressed on B cells, monocytes, T cell clones, and weakly on granulocytes. It exhibits ecto-ATPase activity and is upregulated on activated T and B cells.

For Research Use Only. Not for use in diagnostic procedures.

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