Thermo Fisher Scientific Mouse IL-18 Recombinant Protein
마우스 IL-18 재조합 단백질로, E. coli에서 발현된 고순도(>90%) 제품입니다. IFN-γ 유도 활성 검증 완료. 엘라이자, 기능 분석, 대조군 실험 등에 사용됩니다. 동결건조 형태로 제공되며, 재구성 후 단기 냉장·장기 -80°C 보관 권장.
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- Protein
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Applications
- ELISA (ELISA): Assay-dependent
- Functional Assay (Functional): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | Mouse IL-18, amino acids 36–192 of the mature sequence |
| Molecular Weight | 18 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >90% by SDS-PAGE |
| Endotoxin Concentration | <0.1 ng/µg |
| Activity | Determined by the dose-dependent induction of IFN-gamma production in mouse IL-18 receptor transfected KG-1 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Storage Buffer | PBS with 0.1% BSA, 1% sucrose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Wet or Dry ice (international) |
Product Specific Information
Reconstitution:
Briefly centrifuge vial before opening. Reconstitute with 250 µL of ice-cold, sterile, distilled water on ice.
Storage:
Store lyophilized product at -20°C, preferably desiccated. After reconstitution, store at 2–8°C for up to one week. For long-term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.
Target Information
The protein encoded by this gene is a proinflammatory cytokine that induces IFN-gamma production in T cells. In combination with IL-12, it inhibits IL-4–dependent IgE and IgG1 production while enhancing IgG2a production in B cells. IL-18 binding protein can interact with this cytokine and negatively regulate its biological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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