Thermo Fisher Scientific BAFF Monoclonal Antibody, PeproTech
BAFF 단백질을 인식하는 Mouse monoclonal 항체로, Western blot, ELISA, Flow cytometry에 적합합니다. Human 시료에 반응하며, Protein G로 정제된 Lyophilized 형태입니다. B세포 활성화 연구 및 BAFF 관련 신호전달 분석에 활용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.25–0.50 µg/mL | - |
| Flow Cytometry (Flow) | - | View 1 publication |
| ELISA | 5.0–6.0 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | E.coli-derived Recombinant Human BAFF (BAFF (BLyS), UniProt ID: Q9Y275-1, antigen range: 134–285) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
| RRID | AB_3074167 |
Product Specific Information
AA Sequence of recombinant protein:
AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL
Preparation:
Produced in mice immunized with highly pure Recombinant Human BAFF. Anti-Human BAFF-specific antibody was purified from cell culture by Protein G affinity chromatography.
Target Information
BAFF is a membrane-bound cytokine expressed by B cell lineage cells. The soluble form binds to receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF acts as a potent B cell activator, essential for B cell proliferation and differentiation. It is also expressed by T lymphocytes and promotes T cell activation and survival. Isoforms resulting from alternative splicing and glycosylation have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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