Thermo Fisher Scientific SERPINC1 Polyclonal Antibody, MaxPab
SERPINC1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 유래 단백질에 반응하며, 비결합형 액상 형태입니다. 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4) 버퍼에 보존됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- H00000462-D01P
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SERPINC1 (AAH22309.1, 1 a.a. ~259 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MYSNVIGTVT SGKRKVYLLS LLLIGFWDCV TCHGSPVDIC TAKPRDIPMN PMCIYRSPEK KATEDEGSEQ KIPEATNRRV WELSKANSRF ATTFYQHLAD SKNDNDNIFL SPLSISTAFA MTKLGACNDT LQQLMEVFKF DTISEKTSDQ IHFFFAKLNC RLYRKANKSS KLVSANRLFG DKSLTFNDLY VSDAFHKAFL EVNEEGSEAA ASTAVVIAGR SLNPNRVTFK ANRPFLVFIR EVPLNTIIFM GRVANPCVK
Target Information
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily.
It inhibits thrombin and other activated serine proteases of the coagulation system, regulating the blood coagulation cascade.
The protein includes two functional domains:
- Heparin binding domain at the N-terminus of the mature protein
- Reactive site domain at the C-terminus
The inhibitory activity is enhanced by the presence of heparin.
More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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