Thermo Fisher Scientific TCP1 Polyclonal Antibody
Human TCP1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 IHC(Paraffin) 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공. PBS 기반 버퍼에 40% glycerol 포함, 장기 보관 시 -20°C 권장.
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TCP1. Recombinant protein control fragment (Product #RP-94733) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790337 |
Product Specific Information
Immunogen sequence:
VRYINENLIV NTDELGRDCL INAAKTSMSS KIIGINGDFF ANMVVDAVLA IKYTDIRGQP RYPVNSVNIL KAHGRSQMES MLISGY
Target Information
The T Complex Polypeptide 1 (TCP-1) is approximately 60 kDa protein constitutively expressed in almost all eukaryotic cells and is upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone involved in the folding of actin and tubulin.
Chaperonins recognize and stabilize polypeptide intermediates during folding, assembly, and disassembly, sharing characteristics with Heat Shock Protein 70 (HSP70) such as high abundance, stress induction, and ATPase activity.
The chaperonin family includes mitochondrial HSP60, E. coli GroEL, plastid Rubisco-subunit binding protein, and archaebacterial TF55. The TCP-1 sequence shows nearly 40% identity to TF55 but only minimal similarity to HSP60 and GroEL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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