Thermo Fisher Scientific ZNF25 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZNF25. Recombinant protein control fragment (Product #RP-95529). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZNF25,uniProtId:P17030-1,ncbiNodeId:9606,antigenRange:41-128,antigenLength:456,antigenImageFileName:PA5-56391_ZNF25_P17030-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56391_ZNF25_P17030-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2650020

Product Specific Information

Immunogen sequence: YSHLVSVGYH VNKPNAVFKL KQGKEPWILE VEFPHRGFPE DLWSIHDLEA RYQESQAGNS RNGELTKHQK THTTEKACEC KECGKFFC

Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 55%.

Target Information

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF25 (Zinc finger protein 25), also known as Zinc finger protein KOX19, is a 456 amino acid nuclear protein that contains one KRAB domain and twelve C2H2-type zinc fingers. The gene encoding ZNF25 maps to a region of human chromosome 10 that has been a loci of interest for multiple endocrine neoplasia type 2A and 2B. There are two isoforms of ZNF25 that are produced as a result of alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.