Thermo Fisher Scientific ZNF25 Polyclonal Antibody
Human ZNF25 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 완충액에 보관. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZNF25. Recombinant protein control fragment (Product #RP-95529). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2650020 |
Product Specific Information
Immunogen sequence:
YSHLVSVGYH VNKPNAVFKL KQGKEPWILE VEFPHRGFPE DLWSIHDLEA RYQESQAGNS RNGELTKHQK THTTEKACEC KECGKFFC
Highest antigen sequence identity to the following orthologs:
- Mouse: 55%
- Rat: 55%
Target Information
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass transcriptional activation or repression. Most zinc-finger proteins contain a Kruppel-type DNA-binding domain and a KRAB domain, which interacts with KAP1 to recruit histone-modifying proteins.
ZNF25 (Zinc finger protein 25), also known as Zinc finger protein KOX19, is a 456 amino acid nuclear protein containing one KRAB domain and twelve C2H2-type zinc fingers. The gene encoding ZNF25 is located on human chromosome 10, a region associated with multiple endocrine neoplasia type 2A and 2B. Two isoforms of ZNF25 are produced due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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