Thermo Fisher Scientific PGAM1 Polyclonal Antibody
Thermo Fisher Scientific의 PGAM1 Polyclonal Antibody는 Western blot에 적합한 염소 유래 IgG 항체입니다. 인간 유래 합성 펩타이드로 면역화되었으며, 액상 형태로 제공됩니다. PGAM1 단백질의 당대사 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.03–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide KAMEAVAAQGKAKK (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2160788 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX22220-PEP).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PGAM1 belongs to the phosphoglycerate mutase family. It is an important component of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway.
PGAM1 is a dimeric enzyme containing, in different tissues, varying proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB).
Mutations in PGAM1 cause muscle phosphoglycerate mutase deficiency, also known as glycogen storage disease X.
Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified using conventional chromatography techniques.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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