Thermo Fisher Scientific FBXO33 Polyclonal Antibody
FBXO33 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A 정제 및 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human FBXO33, amino acids 331–430 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FBXO33 is the substrate recognition component of the SCF (SKP1–CUL1–F-box protein) E3 ubiquitin-protein ligase complex, which mediates ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 likely recognizes and binds phosphorylated target proteins such as YBX1. Members of the F-box protein family, including FBXO33, contain an approximately 40-amino acid F-box motif that mediates interaction with SKP1. SCF complexes act as protein-ubiquitin ligases, with F-box proteins linking SKP1 and specific ubiquitination targets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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