Thermo Fisher Scientific Cytokeratin 16 (KRT16) Monoclonal Antibody (KRT16, 1714)
인간 Cytokeratin 16 단백질을 인식하는 Mouse IgG1 단클론 항체. IHC(P)에서 0.1–0.2 µg/mL 농도로 사용 가능. 단백질 A/G로 정제, PBS/BSA buffer에 보존. 4°C 보관, 연구용 전용.
- 카탈로그번호
- 3868-MSM2-P1
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 0.1–0.2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT16, 1714 |
| Immunogen | Recombinant fragment from the C-terminal of human Cytokeratin 16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- For formalin-fixed tissues: Heat tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, then cool at room temperature for 20 min.
Target Information
KRT16 is a member of the keratin gene family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12–q21.
KRT16 is coexpressed with keratin 14 in epithelial tissues such as esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma, and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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