Thermo Fisher Scientific PDCD6 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is greater than 95% as verified by SDS-PAGE.

Target Information

An increased intracellular Ca²⁺ concentration induces apoptotic cell death. Transiently elevated Ca²⁺ concentrations are required for glucocorticoid-mediated and T-cell receptor-mediated pathways, leading to T-cell apoptosis. ALG-2 (apoptosis-linked gene 2) is a Ca²⁺-binding protein involved in late regulatory events of apoptosis where multiple death signals converge. ALG-2 is expressed in normal brain and more abundantly in ischemic brain. The protein contains five EF-hand-like motifs and shares homology with the penta EF-hand family, including Calpain small subunits sorcin and Grancalcin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음 – OCR 텍스트만 통합됨)