Thermo Fisher Scientific PNK Polyclonal Antibody
PNK 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 고순도 항원 친화 크로마토그래피 정제. DNA 손상 복구 연구용에 적합. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PNKP (1–521 aa, UniProt ID: Q96T60-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720719 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Anti-human Polynucleotide Kinase (PNK) Polyclonal Antibody recognizes a 57 kDa nuclear enzyme involved in DNA strand repair processes during replication, recombination, and in response to DNA damage. PNK phosphorylates and dephosphorylates DNA termini (5'-hydroxy and 3'-phosphate) to facilitate repair by DNA polymerase-beta and DNA ligase III. It is a key component in maintaining genomic stability in human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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