Thermo Fisher Scientific FOXJ1 Polyclonal Antibody
FOXJ1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(Paraffin) 응용에 적합. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용 가능.
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- PA536210
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 264–315 of human FOXJ1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2553418 |
Product Specific Information
- Detects endogenous FOXJ1 protein at a molecular weight of approximately 45 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Forkhead-box J1 (FOXJ1) is a 421-amino acid transcription factor that suppresses T cell activity and spontaneous autoimmunity by repressing NF-κB activity. It also inhibits humoral immune responses in B cells. FOXJ1 deficiency leads to spontaneous germinal center formation and is implicated in autoimmune and inflammatory diseases. Additionally, FOXJ1 is essential for cilia formation and left-right axis determination by regulating calpastatin expression, aiding basal body anchoring to the apical cytoskeleton. FOXJ1 expression may serve as an early marker of epithelial cell differentiation and recovery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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