Thermo Fisher Scientific CD89 Monoclonal Antibody (A59)
CD89 단백질을 인식하는 마우스 모노클로날 항체(A59 클론). 인간 및 비인간 영장류 시료에 반응. Flow Cytometry에 적합하며, Protein A로 정제된 액상 형태. 4°C 보관, 동결 금지.
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Applications
- Flow Cytometry (Flow): 1–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human, Non-human primate, Rhesus monkey |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A59 |
| Immunogen | Ag8.653 myeloma cells (Target: CD89 (FCAR), UniProt ID: P24071-1, Antigen range: 1–287) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745507 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD89, a 55–100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes, and macrophages.
Target Information
This gene encodes a receptor for the Fc region of IgA, belonging to the immunoglobulin gene superfamily. The receptor is a transmembrane glycoprotein expressed on myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils. It mediates immune responses to pathogens through IgA-opsonized targets, triggering processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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