Thermo Fisher Scientific RB1 Polyclonal Antibody
RB1 단백질을 검출하기 위한 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합함. 인간, 생쥐, 랫트 반응성. 고순도 Affinity chromatography 정제, PBS/glycerol 저장, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RB1 (Accession P06400), corresponding to amino acid residues S588–T638 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900473 |
Product Specific Information
Antibody detects endogenous levels of total Retinoblastoma.
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine residues but not on tyrosine. It forms complexes with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may regulate transcription, and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of the breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-115839_Rb_P06400-1_Rabbit.svg, PA5-115839_Rb_P06400-1_Rabbit_PDP.jpeg)
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