Thermo Fisher Scientific DTYMK Monoclonal Antibody (OTI1E6), TrueMAB
DTYMK 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간 DTYMK full-length recombinant protein을 면역원으로 사용하였으며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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- CF503491
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E6 |
| Immunogen | Full length human recombinant protein of human DTYMK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis.
DTYMK is essential for DNA synthesis and acts as a key intermediate enzyme in the metabolism of pyrimidine analog drugs such as 5-Fluorouracil (5-FU), a chemotherapeutic agent used for various solid tumors.
The human DTYMK gene was identified via functional complementation of a Saccharomyces cerevisiae cell cycle mutant (cdc8). DTYMK mRNA and enzyme activity are regulated by cell cycle and growth pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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