ELK Biotechnology KTNB1 rabbit pAb
KTNB1 단백질을 인식하는 rabbit polyclonal 항체로, WB, ELISA, IHC에 적합합니다. 인간 및 마우스 시료에 반응하며, 세포질 및 방추체 중심체에 주로 위치합니다. 고순도 IgG 형 항체로 -20°C에서 1년 보관 가능합니다.
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제품명
KTNB1 rabbit pAb
적용 분야
- WB
- ELISA
- IHC
권장 희석 배율
- WB: 1:500–2000
- IHC-p: 1:50–300
- ELISA: 1:2000–20000
제품 정보
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from human KTNB1 (AA range: 72–122) |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 10300 |
| Human Swiss-Prot No | Q9BVA0 |
| Species Reactivity | Human; Mouse |
세포 내 위치
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles (PubMed:9658175). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (PubMed:26929214).
배경 정보
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A1) and an 80 kDa accessory protein (p80 subunit B1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008]
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