ELK Biotechnology Ku-80 rabbit pAb
Ku-80 단백질을 인식하는 토끼 폴리클로날 항체로, DNA 이중가닥 절단 복구 연구에 적합. IHC, IF, WB에 사용 가능하며 인간, 생쥐, 랫드에 반응. 핵 및 염색체에서 발현되는 단백질 검출에 유용. -20°C에서 1년 보관 가능.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology Ku-80 rabbit pAb
ELK Biotechnology Ku-80 Rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Ku-80 rabbit pAb |
| Alternative Names | X-ray repair cross-complementing protein 5 (EC 3.6.4.-; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)) |
| Applications | IHC, IF, WB |
| Recommended Dilutions | IHC-p: 1:50–200, WB: 1:500–2000 |
| Immunogen | Synthesized peptide derived from human Ku-80 |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 82 kDa |
| Gene ID (Human) | 7520 |
| Human Swiss-Prot No. | P13010 |
| Cellular Localization | Nucleus, nucleolus, chromosome |
| Species Reactivity | Human, Rat, Mouse |
Background
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase and functions together with the DNA ligase IV–XRCC4 complex in the repair of DNA double-strand breaks by non-homologous end joining and in the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in the ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. (RefSeq, Jul 2008)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.