ELK Biotechnology M-CSF Receptor (phospho-Tyr546) rabbit pAb
M-CSF Receptor (phospho-Tyr546) rabbit polyclonal antibody로, 인간 및 마우스 시료에 반응합니다. WB, ELISA, IHC에 적합하며, 세포막 단백질의 인산화 상태 분석에 유용합니다. 고순도 IgG, 1 mg/ml 농도로 제공됩니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology M-CSF Receptor (phospho-Tyr546) rabbit pAb
ELK Biotechnology M-CSF Receptor (phospho-Tyr546) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | M-CSF Receptor (phospho-Tyr546) rabbit pAb |
| Alternative Names | Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115) |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized phospho peptide around human M-CSF Receptor (Tyr546) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 107 kDa |
| Gene ID (Human) | 1436 |
| Human Swiss-Prot No. | P07333 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine that controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, biological effects of this cytokine. Ligand binding activates the receptor kinase through oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and a member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. (RefSeq, Dec 2013)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.