Thermo Fisher Scientific HSP27 Recombinant Rabbit Monoclonal Antibody (SAIC-23B-22)
Thermo Fisher Scientific의 HSP27 Recombinant Rabbit Monoclonal Antibody (SAIC-23B-22)은 인간 HSPB1을 특이적으로 인식하는 항체로, Western blot, ICC/IF, Flow cytometry 등에 적합합니다. 고순도의 recombinant monoclonal 형태로 제공되며, Protein A 정제 및 안정적 PBS buffer에 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Mass Spectrometry (MS) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAIC-23B-22 |
| Immunogen | Peptide DGVVEITGK derived from Heat shock protein beta-1, involved in stress resistance and actin organisation, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074343 |
Product Specific Information
Specificity: Recognises human HSPB1.
Target Information
In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein which functions as a molecular chaperone that maintains denatured proteins in a folding-competent state. It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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