Thermo Fisher Scientific HSP27 Recombinant Rabbit Monoclonal Antibody (SAIC-23E-30)
Recombinant rabbit monoclonal antibody specific for human HSP27 (HSPB1). Suitable for ICC/IF and MS applications. High purity Protein A-purified liquid form. Stable storage at 4°C or -20°C. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:100 |
| Mass Spectrometry (MS) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAIC-23E-30 |
| Immunogen | Peptide LFDQAFGLPR derived from Heat shock protein beta-1 (aa 28–37), conjugated to KLH. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074345 |
Product Specific Information
Specificity: Recognises human HSPB1.
Target Information
Cells respond to environmental stress by increasing expression of heat shock proteins. HSPB1 (heat shock protein beta-1 or HSP27) functions as a molecular chaperone, maintaining denatured proteins in a folding-competent state. It plays roles in stress resistance and actin organization, and regulates processes such as phosphorylation and axonal transport of neurofilament proteins. Mutations in HSPB1 can lead to Charcot-Marie-Tooth disease 2F and distal hereditary motor neuronopathy type 2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: MA5-47901_HSP27_P04792-1_Rabbit.svg, MA5-47901_HSP27_P04792-1_Rabbit_PDP.jpeg)
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