Thermo Fisher Scientific HOXD11 Monoclonal Antibody (5G4)
Human HOXD11 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot과 ELISA에 적합합니다. PBS 기반 액상 형태이며, 보존제가 포함되지 않습니다. 연구용으로만 사용되며, 세포 핵 내 HOXD11 단백질 연구에 유용합니다.
- 카탈로그번호
- H00003237-M03J
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HOXD11 Monoclonal Antibody (5G4)
Applications
Western Blot (WB)
- Assay-Dependent
ELISA
- 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5G4 |
| Immunogen | HOXD11 (NP_067015, 1–76 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MNDFDECGQS AASMYLPGCA YYVAPSDFAS KPSFLSQPSS CQMTFPYSSN LAPHVQPVRE VAFRDYGLER AKWPYR
Target Information
HOX11, also called homeobox11 or Tcl-3, is located at the 10q24 T-cell translocation breakpoint region.
It encodes a homeobox-domain containing protein with a glycine and proline-rich amino terminus.
HOX11 is required for spleen development and cell survival. The protein binds specific DNA sequences and localizes to the nucleus, functioning as a transcription activator.
HOX11 gene is highly expressed in T-ALLs due to translocations such as t(7;10)(q35;q24) or t(10;14)(q24;q11).
This deregulation leads to activation of tumor-associated target genes, and HOX11 gene translocation is linked to T-cell leukemia and lymphoid neoplasias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.