Thermo Fisher Scientific HOXC12 Monoclonal Antibody (1C6)
HOXC12 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 ELISA에 적합합니다. Human, Mouse, Rat에 반응하며, IgG2a 아이소타입을 가진 비결합 항체입니다. 연구용으로만 사용 가능합니다.
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- H00003228-M01
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C6 |
| Immunogen | HOXC12 (NP_776272, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGEHNLLNPG FVGPLVNIHT GDTFYFPNFR ASGAQLPGLP SLSYPRRDNV CSLSWPSAEP CNGYPQPYLG SPVSLNPPFG RTCELARVED GKGYYREPCA
Target Information
The Homeobox (Hox) proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias, and hereditary malformations.
In mammals, there are four gene clusters encoding Hox proteins: HoxA, HoxB, HoxC, and HoxD, each consisting of 9–11 tandemly arranged genes located on different chromosomes.
HoxC12 (Homeobox C12), also known as Hox3, Hox3F, or HOC3F, is a member of the Abd-B homeobox (Hox) family and is encoded by a gene from the HoxC cluster. HoxC12 is a 282 amino acid long nuclear protein containing one homeobox DNA-binding domain.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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