Thermo Fisher Scientific H2AK119ub Polyclonal Antibody
다양한 응용 분야(WB, ICC/IF, Flow, ELISA, ChIP)에 사용 가능한 Rabbit Polyclonal 항체. 인간 H2AK119ub 단백질에 특이적이며 Monkey, Pig, Cat에서도 반응 예측. 고순도 친화 크로마토그래피 정제, 안정한 액상 형태로 장기 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| Flow Cytometry (Flow) | 2–4 µg/1×10⁶ cells |
| ELISA | 0.15–10 µg/mL |
| ChIP assay (ChIP) | 1–2 µg × 10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to Human HIST1H2AA (aa 116–124) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605927 |
Product Specific Information
This antibody is predicted to react with Monkey, Pig, and Cat.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction into higher-order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts lack polyA tails and contain a palindromic termination element. This gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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