Thermo Fisher Scientific PRMT6 Polyclonal Antibody
Rabbit polyclonal antibody against PRMT6 for WB and ICC/IF applications. Reacts with human, mouse, and rat. Affinity purified, supplied in PBS with glycerol and BSA. For research use only.
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- 720142
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human PRMT6 (aa 37–49, 358–375) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at –20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633196 |
Product Specific Information
These polyclonal antibodies are of rabbit origin and developed by immunizing animals with specific proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in relevant research applications.
This antibody is developed for Research Use Only and is non-hazardous and non-infectious.
Predicted to react with Monkey, Pig, and Rat.
Target Information
Protein arginine N-methyltransferase 6 (PRMT6) demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on recombinant glycine- and arginine-rich substrates.
Acts as a transcriptional coactivator of several steroid hormone receptors including ESR1, ESR2, PGR, and NR3C1.
Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator.
May play a role in innate immunity against HIV-1 by methylating and impairing the function of viral proteins such as Tat, Rev, and Nucleocapsid protein p7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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