Thermo Fisher Scientific Angiotensinogen Polyclonal Antibody
Thermo Fisher Scientific의 Angiotensinogen 폴리클로날 항체로, 마우스 및 랫트 시료에 반응. WB 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 연구용으로 혈압 조절 관련 단백질 분석에 활용 가능.
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- PA578740
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived mouse Angiotensinogen recombinant protein (Position: D25–A115) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2745856 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The protein encoded by AGT (angiotensinogen precursor) is expressed in the liver and cleaved by renin when blood pressure decreases. The resulting angiotensin I is further processed by angiotensin-converting enzyme (ACE) to form angiotensin II, which plays a key role in blood pressure regulation.
Mutations in this gene are linked to essential hypertension, renal tubular dysgenesis, atrial fibrillation, and inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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