Thermo Fisher Scientific Rex1 Recombinant Rabbit Monoclonal Antibody (14H16L9)
Rex1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 면역세포염색에 최적화됨. 높은 특이성과 민감도를 제공하며, 로트 간 일관성이 우수함. 동물 유래 성분이 없는 포뮬레이션으로 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–3 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 14H16L9 |
| Immunogen | Recombinant protein corresponding to amino acids 1–140 of human REX1 transcription factor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532416 |
Product Specific Information
Intact IgG appears on a non-reducing gel as a ~150 kDa band and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
Rex1 is involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. It is required for efficient elongation of TSIX, a non-coding RNA antisense to XIST, and binds the DXPas34 enhancer within the TSIX promoter. Rex1 also plays a role in embryonic stem cell self-renewal. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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