Thermo Fisher Scientific RGS13 Polyclonal Antibody
RGS13 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 IHC에 사용 가능하며, 인간 시료에 반응합니다. Protein A 정제, PBS/sucrose buffer, -20°C 보관 조건. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.25 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human RGS13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688380 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Horse: 92%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%
Target Information
RGS13 is the smallest member of the mammalian RGS (Regulators of G protein-signaling) family, homologous to yeast SST2 and C. elegans egl-10 proteins. RGS proteins attenuate G protein-mediated pathways by acting as GTPase-activating proteins (GAPs) for Ga subunits.
RGS13 is most abundantly expressed in human tonsil, thymus, lung, lymph node, and spleen. It regulates Gai, Gaq, and Gas coupled signaling cascades and acts as a GTPase-activating protein for Gai and Gao. The protein blocks MAPK activity induced by Gai- or Gaq-coupled receptors and attenuates GTPase-deficient Gaq (GaqQL) mediated cAMP response element activation.
The human RGS13 gene is localized on chromosome 1q31.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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