Thermo Fisher Scientific MRP2 Recombinant Rabbit Monoclonal Antibody (23GB4275)
Western blot, ICC/IF, Flow cytometry에 적합한 MRP2 토끼 단클론 항체. 인간 MRP2 단백질 유래 펩타이드로부터 제작. HEK293F 발현 시스템 사용, Affinity chromatography로 정제. PBS/glycerol buffer에 보존, 연구용 전용.
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- MA55267x (2개 옵션)
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4275 |
| Immunogen | A synthesized peptide derived from human MRP2 (1500–1545 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions.
The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, an SH3 motif, and a guanylate kinase domain. It interacts with various cytoskeletal and cell junctional proteins, potentially regulating cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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