Thermo Fisher Scientific RSV Fusion Protein Monoclonal Antibody (RSV3216)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Flow Cytometry (Flow)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

-

Immunomicroscopy (IM)

Assay-dependent

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

RSV3216

Immunogen

Bovine RSV strains: 127, SNK and 9007. Human RSV strains: Long, Randall, 8/60, and A/2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.5

Contains

<0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_935311

Product Specific Information

Suitable as capture reagent with MA1-80039 as detection reagent in sandwich ELISA.

Purity is >90% IgG.

Mouse anti respiratory syncytial virus fusion protein antibody, clone RSV3216 recognizes an epitope within the RSV fusion protein (46 kDa and 22 kDa s-s linked glycoprotein).

Target Information

Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps. Its genome consists of single stranded, negative sense RNA that encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. Its name comes from the fact that F proteins on the surface of the virus cause the membranes on nearby cells to merge, forming syncytia. While RSV typically produces mild symptoms in adults, it is one of the leading causes of lower respiratory tract infections and hospital visits during infancy and childhood.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.