Thermo Fisher Scientific CD91/LDL Receptor Related Protein 1 (LRP1) Monoclonal Antibody (LRP1/6784)
인간 LRP1 단백질을 인식하는 마우스 단클론 항체로, IHC(P)에서 1-2 µg/mL 농도로 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관. 세포 내 신호전달 및 지질 항상성 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LRP1/6784 |
| Immunogen | Recombinant fragment of human LRP1 protein (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Brain, lung, or human liver tissue
- Cellular Location: Cytoplasm, nucleus, and cell surface
Target Information
The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells.
It is also necessary for A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer’s disease.
Expression of this gene decreases with age and is lower in brain tissue from Alzheimer patients compared to controls.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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