Thermo Fisher Scientific CAMK2N1 Polyclonal Antibody
CAMK2N1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, Human 및 Mouse 시료에서 반응. 단백질 A 및 항원 친화 크로마토그래피로 정제. 연구용으로만 사용 가능.
- 카탈로그번호
- PA523740
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 37–65 amino acids from the C-terminal region of human CAMK2N1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4 °C short term. For long term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541240 |
Product Specific Information
This antibody is predicted to react with bovine and rat based on sequence homology.
Target Information
Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity). Plays a role in the maintenance of long-term retrieval-induced memory in response to contextual fear (By similarity). Modulates blood pressure and vascular reactivity via regulation of CAMK2 activity and left ventricular mass (By similarity). Mediates the NLRP3 inflammasome in cardiomyocytes by inhibiting the MAPK14/p38 and MAPK8/JNK pathways, regulating ventricular remodeling and cardiac rhythm post-myocardial infarction (By similarity). Negatively affects insulin sensitivity and promotes lipid formation in adipose tissues independent of CAMK2 signaling (By similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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