Thermo Fisher Scientific FGFR4 Monoclonal Antibody (19H3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

19H3

Immunogen

Cytoplasmic domain of human FGFR4 fused to maltose binding protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2539467

Product Specific Information

This target has a predicted molecular weight of 88 kDa. Actual Western blot results show a band at 105 kDa.

Target Information

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.