Thermo Fisher Scientific FGFR4 Monoclonal Antibody (19H3)
FGFR4 단백질을 특이적으로 인식하는 Mouse monoclonal antibody (Clone 19H3). Western blot과 Immunoprecipitation에 사용 가능. 인간 FGFR4의 세포질 도메인을 면역원으로 제작. 1 mg/mL 액상 형태로 제공되며, 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FGFR4 Monoclonal Antibody (19H3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 19H3 |
| Immunogen | Cytoplasmic domain of human FGFR4 fused to maltose binding protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539467 |
Product Specific Information
This target has a predicted molecular weight of 88 kDa. Actual Western blot results show a band at 105 kDa.
Target Information
FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family regulates various cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family is implicated in several diseases such as cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of CYP7A1 expression, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. It also plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.