Thermo Fisher Scientific RBL1 Polyclonal Antibody
RBL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC(frozen), IP에 사용 가능. Human, Mouse, Rat 반응성. PBS 기반 용액 형태로 제공되며 4°C 보관. 세포주 SK-BR-3, NIH/3T3에 양성 대조로 권장.
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Thermo Fisher Scientific RBL1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (Human, C terminal) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2175417 |
Product Specific Information
Recommended positive controls: SK-BR-3 and NIH / 3T3 lysate.
Target Information
RB-like 1 is similar in sequence and possibly in function to the retinoblastoma 1 (RB1) gene product. RB1 is a tumor suppressor protein involved in cell cycle regulation, being phosphorylated during the S to M phase transition and dephosphorylated in the G1 phase. Both RB1 and RB-like 1 can form complexes with adenovirus E1A and SV40 large T-antigen, binding only in the unphosphorylated form. These proteins inhibit transcription of cell cycle genes containing E2F binding sites, suggesting RB-like 1 may also act as a tumor suppressor.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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