Thermo Fisher Scientific PRMT2 Polyclonal Antibody
Human PRMT2 단백질을 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에 적합. KLH 결합 합성 펩타이드(22-53aa)로 면역화. 고순도 Protein G 정제, 2 mg/mL 농도, PBS 및 sodium azide 포함. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 22–53 amino acids from the N-terminal region of human PRMT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2171645 |
Product Specific Information
PA1-30272 detects PRMT2 from human samples.
Target Information
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, and histone H4.
Acts as a coactivator (with NCOA2) of androgen receptor (AR)-mediated transactivation and as a coactivator of estrogen receptor (ER)-mediated transactivation.
Enhances PGR, PPARG, and RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis.
Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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