
Thermo Fisher Scientific TBK1 Monoclonal Antibody (108A429)
TBK1 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot, IHC, ICC/IF에 사용 가능. 다양한 종에 반응하며, Protein G로 정제된 액상 형태. NF-κB 및 IRF3 신호전달 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:20 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat, Bovine, Dog, Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 108A429 |
| Immunogen | Synthetic peptide corresponding to amino acids 563–577 (YYQFKKDKAERRLAYC) of human TBK1 (NP_037386) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_559588 |
Product Specific Information
MA1-20344 detects NAK in human samples.
Target Information
TBK1 (TANK-binding kinase 1) is a serine/threonine kinase belonging to the IKK family, involved in NF-κB activation and IRF3 signaling. It acts as a key mediator of immune and inflammatory gene expression. TBK1 phosphorylates IKKβ and activates NF-κB in response to growth factors and PMA, functioning upstream of NIK and the IKK complex. It plays a critical role in protecting embryonic liver from apoptosis.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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배송 정보
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