
Thermo Fisher Scientific Pembrolizumab Monoclonal Antibody (1D6E10)
Pembrolizumab(1D6E10) 단클론 항체로 PD-1과 PD-L1 결합을 차단하여 T세포 면역반응을 활성화. 인간 반응성, Mouse IgG1/kappa 아이소타입. ELISA에 적합하며 Lyophilized 형태로 제공. 연구용으로만 사용.
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Applications
Tested Dilution
- ELISA: 0.01–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D6E10 |
| Immunogen | Pembrolizumab |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Pembrolizumab (Keytruda) is a humanized monoclonal antibody approved by the U.S. FDA for the treatment of patients with unresectable or metastatic melanoma. It binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.
GenScript Anti-Pembrolizumab Antibody (1D6E10), mAb, Mouse is produced from a hybridoma resulting from the fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Pembrolizumab.
Target Information
Pembrolizumab (Keytruda) is a humanized monoclonal antibody approved by the U.S. FDA for the treatment of patients with unresectable or metastatic melanoma. It binds to PD-1 and blocks its interaction with PD-L1, activating T-cell-mediated immune responses against tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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