Thermo Fisher Scientific CYP24A1 Polyclonal Antibody
CYP24A1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 분석에 적합합니다. 1.46 mg/mL 농도의 액상 형태이며, 단기 4°C, 장기 -20°C 보관이 권장됩니다. 비결합(Unconjugated) 상태로 공급되며, 다양한 세포주에 대한 양성 대조군으로 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Dog |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 241–514 of CYP24A1 (Uniprot ID: Q07973) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.46 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11154312 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (87%), Rat (88%), Pig (90%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the active form of vitamin D3, by hydroxylation of the side chain.
In regulating vitamin D3 levels, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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