Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI1E3), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex, which includes elongins A/A2, B, and C. This complex enhances RNA polymerase II elongation by reducing transient pausing during transcription.
Elongin A acts as the active transcriptional component, while elongins B and C serve regulatory roles. Elongin A2 is testis-specific and forms a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein interacts with elongins B and C, inhibiting transcription elongation.
Western blot analysis using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) targeting unique regions of this protein confirmed consistent molecular weight results.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.