Thermo Fisher Scientific ORAI3 Polyclonal Antibody
ORAI3 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 시료에 반응. WB, IHC, ICC/IF, Flow Cytometry 등 다양한 응용 가능. 액상 형태, 1 mg/mL 농도, PBS 기반 저장용액 포함. 연구용으로만 사용.
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Thermo Fisher Scientific ORAI3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within Human Orai-3 aa 11–60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854682 |
Product Specific Information
Positive Control Samples:
Raji, A549, MG-63, SH-SY-5Y, rat brain tissue, human liver cancer tissue, human kidney tissue, human placenta tissue, mouse testis tissue.
Target Information
ORAI3 is a protein-coding gene involved in calcium signaling and regulation of calcium homeostasis. It belongs to the ORAI family of proteins forming calcium release-activated calcium (CRAC) channels in the plasma membrane. These channels are activated by depletion of calcium from the endoplasmic reticulum, causing calcium influx into the cytoplasm.
ORAI3 is associated with physiological processes such as T-cell activation, muscle contraction, and neurotransmitter release. Dysregulation of ORAI3 expression or function is linked to immune disorders, cancer, and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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