
Thermo Fisher Scientific SERPINC1 Polyclonal Antibody
Human SERPINC1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow Cytometry에 사용 가능. 고순도 Affinity chromatography 정제, PBS/glycerol buffer에 보관. 혈액응고 관련 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human SERPINC1 aa 150–370 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854677 |
Product Specific Information
Positive Control: HepG2, mouse smooth muscle tissue, mouse lung tissue, H22, rat kidney tissue, human liver tissue, human small intestine tissue.
Target Information
The SERPINC1 gene encodes a plasma protease inhibitor belonging to the serpin superfamily. It inhibits thrombin and other activated serine proteases of the coagulation system, regulating the blood coagulation cascade.
This protein contains two functional domains:
- Heparin-binding domain at the N-terminus
- Reactive site domain at the C-terminus
The inhibitory activity is enhanced by heparin. Over 120 mutations have been identified in this gene, many of which are associated with antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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