Thermo Fisher Scientific Complement C5 Monoclonal Antibody (5E 1D1)
인간 Complement C5a에 특이적인 마우스 단클론 항체입니다. ELISA에 적합하며 보존제가 포함되지 않은 액상 형태입니다. 단백질 A로 정제되었으며 4°C 단기 보관, -20°C 장기 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E 1D1 |
| Immunogen | Recombinant Human Complement C5a Protein (Leu679–Arg751) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785899 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human Complement C5a.
Target Information
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is composed of alpha and beta polypeptide chains linked by a disulfide bridge. An activation peptide, C5a, is an anaphylatoxin with potent spasmogenic and chemotactic activity, derived from the alpha chain via cleavage with a convertase. The C5b cleavage product can form a complex with complement component C6, forming the basis of the membrane attack complex.
Mutations in this gene cause complement component 5 deficiency, leading to susceptibility to severe recurrent infections, and have also been linked to liver fibrosis and rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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