Thermo Fisher Scientific Human LRRFIP1 Synthetic Peptide
Human LRRFIP1 단백질의 C-말단 19 아미노산 서열을 기반으로 한 합성 펩타이드입니다. PA5-21114 항체의 블로킹 펩타이드로 사용 가능하며, 인간 단백질 연구용으로 적합합니다. 액상 형태, 200 µg/mL 농도, PBS 버퍼에 보관됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 19 amino acid sequence near the carboxy terminus of human LRRFIP1.
PEP-1228 can be used as a blocking peptide with polyclonal antibody PA5-21114.
Target Information
Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein that mediates either induction or repression of TLR signaling.
Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity.
It also binds the TNF- -308 promoter polymorphism site, suggesting its possible role in regulating TNF production.
FLAP-1, along with LRRFIP2 and FLIIH, helps coordinate inflammatory responses after infection and may serve as a novel target in controlling agonist-induced TLR-mediated inflammatory and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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