Thermo Fisher Scientific Human LRRFIP2 Synthetic Peptide
Human LRRFIP2 단백질의 C-말단 근처 17개 아미노산으로 구성된 합성 펩타이드입니다. PA5-21115 항체의 블로킹 펩타이드로 사용 가능하며, 정제된 액상 형태로 제공됩니다. PBS(pH 7.2) 버퍼에 0.1% BSA와 0.02% sodium azide를 포함하며, -20°C에서 보관합니다.
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Thermo Fisher Scientific Human LRRFIP2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 17 amino acid sequence near the carboxy terminus of human LRRFIP2.
PEP-1229 can be used as a blocking peptide with polyclonal antibody PA5-21115.
Target Information
The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), similar to LRRFIP1, was identified through a yeast two-hybrid system by binding to the LRR domain of human FLI.
LRRFIP2 activates the Wnt signaling pathway in cultured cells and modulates Wnt signaling via interactions with Disheveled, increasing cellular levels and transcriptional activity of beta-catenin.
It also functions as a positive regulator of the TLR4 signaling pathway, activating NF-kappa-B during early host response to LPS stimulation through binding to MyD88. This interaction is regulated by phosphorylation of specific residues in LRRFIP2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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