Thermo Fisher Scientific Adenylate Kinase 4 Recombinant Rabbit Monoclonal Antibody (014)

Applications

ELISA (ELISA)

• Tested Dilution: 1:5,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 1–4 µL/mg of lysate

Product Specifications

Product Specific Information

This antibody is preservative-free. To prevent contamination, it is recommended to add sodium azide (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:

• Improved specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the rabbit immune repertoire

This antibody shows specificity for Human AK4/AK3L1.

Target Information

The Adenylate Kinase 4 (AK4) gene encodes a mitochondrial matrix enzyme belonging to the adenylate kinase family. These enzymes regulate the adenine and guanine nucleotide balance in cells by catalyzing phosphate group transfer among nucleotides.
There are five known vertebrate isozymes, each with tissue-specific and developmentally regulated expression.
A pseudogene is located on chromosome 17, and three transcript variants encoding the same protein have been identified.
Sequence alignment indicates the gene (NM_013410, NM_203464, NM_001005353) is located on chromosome 1.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.