Thermo Fisher Scientific POLR3K Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human POLR3K. Recombinant protein control fragment (Product #RP-89380). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:POLR3K,uniProtId:Q9Y2Y1-1,ncbiNodeId:9606,antigenRange:6-108,antigenLength:108,antigenImageFileName:PA5-52220_POLR3K_Q9Y2Y1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52220_POLR3K_Q9Y2Y1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645775

Product Specific Information

Immunogen sequence: PGCGNGLIVE EGQRCHRFAC NTCPYVHNIT RKVTNRKYPK LKEVDDVLGG AAAWENVDST AESCPKCEHP RAYFMQLQTR SADEPMTTFY KCCNAQCGHR WRD

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Target Information

Eukaryotes produce 3 distinct classes of RNA polymerase, Pol I, II and III. Each polymerase is responsible for the synthesis of a different class of RNA. RNA polymerase III (Pol III) transcribes the 5S rRNA genes and all of the tRNA (transfer RNA) genes. POLR3K, also known as DNA-directed RNA polymerase III subunit RPC11, is a 108 amino acid nuclear protein that is one of the seventeen subunits that comprise Pol III. Specifically, POLR3K is a DNA-dependent RNA polymerase that uses the four ribonucleoside triphosphates to catalyze the transcription of DNA to RNA. The gene encoding POLR3K maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs and is associated with a variety of genetic disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.