Thermo Fisher Scientific POLR3K Polyclonal Antibody
Human POLR3K 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot과 IHC(P)에서 검증됨. Antigen affinity chromatography로 정제된 액상 형태. 고순도 및 재현성 높은 연구용 시약으로 RNA polymerase III 관련 연구에 적합.
- 판매단위
- pk
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human POLR3K. Recombinant protein control fragment (Product #RP-89380) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2645775 |
Product Specific Information
Immunogen sequence:
PGCGNGLIVE EGQRCHRFAC NTCPYVHNIT RKVTNRKYPK LKEVDDVLGG AAAWENVDST AESCPKCEHP RAYFMQLQTR SADEPMTTFY KCCNAQCGHR WRD
Ortholog sequence identity:
- Mouse: 99%
- Rat: 99%
Target Information
Eukaryotes produce three distinct classes of RNA polymerase: Pol I, II, and III. Each polymerase synthesizes a different class of RNA.
RNA polymerase III (Pol III) transcribes the 5S rRNA genes and all tRNA genes. POLR3K, also known as DNA-directed RNA polymerase III subunit RPC11, is a 108 amino acid nuclear protein and one of the seventeen subunits comprising Pol III.
POLR3K acts as a DNA-dependent RNA polymerase that catalyzes the transcription of DNA to RNA using ribonucleoside triphosphates.
The POLR3K gene is located on human chromosome 16, which encodes over 900 genes and is associated with various genetic disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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