Thermo Fisher Scientific NOP56 Polyclonal Antibody
Thermo Fisher Scientific의 NOP56 Polyclonal Antibody는 인간 NOP56 단백질을 특이적으로 인식하는 토끼 유래 IgG 항체입니다. Western blot, IHC, IP 등 다양한 응용에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 544 and 594 of human NOP56 ribonucleoprotein homolog |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
ErbB4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family is classified into 8 major groups based on sequence comparison of tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
ErbB4 is activated by neuregulins and NTAK, acting as a receptor for heregulin and mediating HGL-stimulated tyrosine phosphorylation. It regulates cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
ErbB4 is predominantly expressed in several breast carcinoma cell lines and normal skeletal muscle, heart, pituitary, brain, and cerebellum. Elevated levels in certain tumor cell lines suggest a role in malignancy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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