
ELK Biotechnology PDE1B rabbit pAb
Human, Rat, Mouse 반응성을 가진 PDE1B rabbit polyclonal antibody로 WB 및 ELISA에 적합. cAMP/cGMP 신호 조절 관련 연구에 활용 가능. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관 가능.
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PDE1B Rabbit Polyclonal Antibody
제품 개요
ELK Biotechnology에서 제공하는 PDE1B rabbit pAb는 cyclic nucleotide phosphodiesterase(PDE) family 중 PDE1 subfamily에 속하는 단백질을 인식하는 항체입니다. PDE1B는 칼모듈린 의존적 효소로서 cAMP와 cGMP 모두에 작용하며, 세포 내 신호 조절에 중요한 역할을 합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product name | PDE1B rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 58 kD |
| GeneID (Human) | 5153 |
| Human Swiss-Prot No. | Q01064 |
| Cellular Localization | Cytoplasm, cytosol |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
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