ELK Biotechnology IF6 rabbit pAb
IF6 rabbit pAb는 인간, 마우스, 랫트 시료에 반응하는 다클론 항체로 WB 및 ELISA에 적합합니다. 세포질과 핵에서 발현되는 단백질을 검출하며, 안정적인 IgG 아이소타입으로 -20°C에서 1년간 보관 가능합니다.
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- ES9001-xxxxx (2개 옵션)
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- pk
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제품명
IF6 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 180–260) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 26 kD |
| Gene ID (Human) | 3692 |
| Human Swiss-Prot No. | P56537 |
| Cellular Localization | Cytoplasm, Nucleus, Nucleolus. Shuttles between cytoplasm and nucleus/nucleolus. |
| Species Reactivity | Human; Mouse; Rat |
Background
Hemidesmosomes are structures that link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. (Provided by RefSeq, Jun 2012)
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